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7 nicotinic acetylcholine receptor: a potential target in treating cognitive decline in schizophrenia

10.1152/physrev.00010.2018 28 BhattiJ

Cells were dehydrated in a series of alcoholic solutions from 70 to 100%, followed by two immersions in propylene oxide for 20 min each, propylene oxide and araldite infiltration for 12 h, at room temperature on a shaking platform

Introducing a second agent with a different mechanism can restart progress by circumventing the specific adaptations the body made in response to the first compound