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GLP- 1's anti-apoptotic and proliferative effects are also mediated by the PI3 K/Akt axis through the transactivation of the epidermal growth factor receptor (EGFR), which is connected to GLP- 1 receptor through c-Src activation and the generation of endogenous EGF like ligands [59]

Food and Drug Administration (FDA) has, for the first time, fully approved a drug that slows the progression of Alzheimers disease

Among the major drugs that are in development, we observe some already in Phase III: inhibitors of the -site amyloid precursor protein cleaving enzyme (BACE) (CNP520, LY3314814, and verubecestat) and antibodies against the A peptide (aducanumab, solanezumab, crenezumab, gantenerumab, and BAN2401) [22, 27]

Drug delivery to the ischemic brain