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Moreover, other specialized mitochondria-residing proteins, such as the apoptosis inducing factor (AIF) and endonuclease G, are translocated to the nuclei following their release from mitochondria and promote peripheral chromatin condensation and high molecular weight DNA fragmentation

As an important source of new drug molecules, natural medicines have many advantages, such as a wide range of biological effects and small toxic and side effects

However, it is important to note that both THC and CBD have many CBR-independent or indirect signaling mechanisms that also contribute to their overall outcomes (Pertwee, 2008

Porcine brain microvessel endothelial cells as an in vitro model to predict in vivo bloodbrain barrier permeability