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Underexplored epigenetic and long-term regulatory mechanisms: Epigenetic regulation of ferroptosis in AKI-to-CKD transition is largely limited to individual molecules (e.g., miRNAs targeting GPX4), with no comprehensive understanding of epigenetic landscapes (e.g., long non-coding RNAs, histone modifications, and DNA methylation) that persistently modulate ferroptosis-related genes during the chronic phase

6.2.2 Potential of active ingredients in future drug development The active ingredients of functional foods are not only used for dietary interventions but also hold great potential to become lead compounds for new drugs

While it is usually harmless, lip pigmentation can impact ones confidence and facial aesthetics since lips play a major role in overall facial harmony and expression