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While metabolomics focuses on identifying and quantifying the metabolites, fluxomics has emerged as the process of studying metabolic fluxes, or the rates of biochemical reactions, in a biological system, which is a more dynamic and quantitative approach to understanding metabolism (Emwas et al., 2022)

doi: 10.18052/www.scipress.com/ILNS.76.72 111 ZaynabM.FatimaM.AbbasS.SharifY.UmairM.ZafarM

Immunosuppressive agents with intrinsic antifungal activity are emerging as candidates for drug repurposing, including calcineurin inhibitors (e.g., cyclosporine, pimecrolimus, tacrolimus/FK506), mTOR inhibitors (e.g., rapamycin), antimetabolites (e.g., mizoribine [MZP], mycophenolic acid [MPA]), and glucocorticoids