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Based on recent changes in international guidelines and the results of a Korean epidemiological study, the recommended age for diabetes screening has been lowered

pH IOP leads to abnormal accumulation of ferrous iron and pro-ferroptotic factors including lipid peroxidation and ACLS4, and depletion of anti-ferroptotic factors, such as GSH, GPX4, and nicotinamide adenine dinucleotide phosphate, in RGC cells and retinas via NCOA4/FTH1 axis, thus disrupting iron metabolism and leading to ferroptosis in RGCs during glaucoma (Yao et al., 2023)

Single-cell-derived clonal lines were screened and confirmed for GLO1 and GLO2 deficiency by sequencing with primers TTCCTAGTTAAGGCGGCACAGG (for GLO1) and ATGAAGGTAGAGGTGCTGCCTGC (for GLO2) and western blot analysis

CID generated two possible sites of glucuronide conjugation