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Clinical Progress of Glutaminase Inhibitors Glutaminase inhibitors selectively target the overactive GLS in cancer cells, sparing GLS2 in normal cells: Blocking EMT (Epithelial-to-Mesenchymal Transition) : These inhibitors can help prevent EMT, which supports cancer spread

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Interestingly, a two-cohort study showed that activated HLA-DR high CD11c high CD14 + monocytes were increased in the PBMCs of patients with mild COVID-19, whereas dysfunctional HLA-DR low CD163 high (indicative of anti-inflammatory function) CD14 + monocytes were observed in severe COVID-19 cases

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