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Biomarker performance was evaluated using receiver operating characteristic (ROC) curve analysis based on exploratory multivariate models, calculating area under the curve (AUC), sensitivity, and specificity

These transform ribulose 5-phosphate into: ribose 5-phosphate, and xylulose 5-phosphate, respectively

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Consistent with these in vitro findings, co-immunoprecipitation assays in G2-synchronized HeLa cells revealed that Myc-tagged Pds5B associated with wild-type Sororin-GFP, but not with the phospho-mimetic Sororin-S145E-GFP mutant (Supplementary Fig