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Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (cblC) 1998

Among the cohort studies, 2 scored three and five points, indicating low-quality studies with high and moderate risk of bias, respectively

Mechanistic Research Perspective Modulation of cellular signaling pathways Regulation of gene expression and epigenetic pathways Investigation of telomerase-associated signaling mechanisms Peptide-protein interaction studies in biochemical research Cellular communication and molecular pathway analysis Primary Research Applications Cellular and Molecular Biology Research: Used to investigate peptide-mediated signaling and regulatory pathways within experimental cell systems

Section specific changes in permeability were also measured ex vivo by Ussing chambers which demonstrated that the ileum had the most dynamic changes