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Jun 20 2022 Mousapour et al., Gastroenterology and Hepatology from Bed to Bench, doi:10.22037/ghfbb.v15i3.2565 Efficacy and Safety of Acetylcysteine for the Prevention of Liver Injury in Covid-19 Intensive Care Unit Patients Under Treatment with Remdesivir: A Double-Blind, Placebo-Controlled Randomized Clinical Trial: Prevention of liver injury in severe Covid-19 pneumonia 2% lower mortality (p=1) , 27% lower ventilation (p=0.57) , 6% greater improvement (p=0.82) , and 5% higher hospital discharge (p=0.8)

There are still several unresolved problems and limitations in this study

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Glutathione and a UV lightinduced glutathione S -transferase are involved in signaling to chalcone synthase in cell cultures