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In order to address this issue, CD133 aptamer has been used to provide targeted delivery of DOX to the liver CSCs with the aim of addressing chemoresistance

Leafy green vegetables, walnuts, flax seeds and fish oils are rich sources of ALA and if you are not eating a lot from these, supplementing with fish oil is a pretty good idea backed by research

In this article, the authors aim to comprehensively review the epidemiology, diagnosis, and management of PSC with emphasis on risk of malignancies and management of PSC