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They have important roles in the maintenance of ECM and adjacent epithelial homeostasis via direct stromal-epithelial contact and the secretion of cytokines [15]

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While methylcobalamin participates in the methylating processes including the synthesis of methionine, the adenosylcobalamin cofactor initiates the transformation of a whole series of substrates into their isomers with an unusual structure [4]

This approach harnesses the power of biological substances like platelet-rich plasma (PRP) and exosome therapy, two cutting-edge alternatives to conventional stem cell treatments