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NSC 79037) is a DNA alkylating agent

The results of the MTT assay showed that overexpression of ATF4 significantly promoted the proliferation of HuOCSCs in vitro and reduced the cell proliferation inhibition rate (Figure 6A)

Popov 5 , (1)Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, (2)The First Affiliated Hospital, Sun Yat-Sen University, (3)Gilead Sciences, Inc., (4)The First Affiliated Hospital of Sun Yat-Sen University, (5)Harvard Medical School, Boston, MA Background: Apoptosis Signal-regulating Kinase 1 (ASK1) is activated by various pathological stimuli and induce cell apoptosis via downstream p38 activation