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Some protocols involve quick infusions, while others take longer to reduce side effects

Then we constructed the double-mutant DK (D82N/K103E) and the enzyme activity of this mutant increased to 430.2% with the best catalytic ability (Fig

Ringleb 7 , Igor Sibon 8 , Omid Halse 2 , Peter Heuschmann 9 , Roland Veltkamp 2,10 , Christian Enzinger 1 1 Department of Neurology, Medical University of Graz, Graz, Austria, 2 Department of Brain Sciences, Imperial College London, London, United Kingdom, 3 Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece, 4 Institute de Biomedicine of Seville, IBiS/Virgen Macarena University Hospital/CSIC/University of Seville, Seville, Spain, 5 Stroke Unit and Division of Cardiovascular Medicine, University of Perugia, Perugia, Italy, 6 Santa Maria della Misericordia Hospital, Perugia, Italy, 7 Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany, 8 Department of Neurology, CHU Bordeaux, Bordeaux University, Bordeaux, France, 9 Institute for Clinical Epidemiology and Biometry (ICE-B), University of Wrzburg, Wrzburg, Germany, 10 Department of Neurology, Alfried-Krupp Krankenhaus, Essen, Germany Background and Aims: Patients with intracerebral haemorrhage (ICH) and atrial fibrillation are at a high risk of ischemic stroke and recurrent ICH

Rollet, M.E