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In PD rat model, Hcy also reduced activity of mitochondrial complex I and caused oxidative stress in the nigrostriatal pathway that were associated with increased production of hydroxyl radicals, reduced glutathione level, and enhanced activity of antioxidant enzymes such as superoxide dismutase and catalase [70]

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Table 5 A clinical study reported the effects of sulforaphane on depression outcomes in cardiac patients with mild to moderate depression