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Glutaminolysis-related genes determine sensitivity to xCT-targeted therapy in head and neck squamous cell carcinoma

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Similarly, in lung fibrosis, inhibition of the Nrf2 pathway is closely associated with elevated levels of oxidative stress in fibrotic tissues, which in turn triggers the abnormal deposition of fibrous components such as collagen, leading to a post-ferroptotic state in lung tissue cells [8, 9]

(12) found significantly higher levels of SOD activity in scalp biopsy tissues of AA patients than in the control group, with the mean level of SOD activity in the early phase being two times higher than in the late phase