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doi: 10.1016/j.bcp.2006.01.002

Nicotinamide riboside supplementation ameliorates ovarian dysfunction in a PCOS mouse model

Plausible mechanisms for STAT3 -enhanced resistance include upregulation of the anti-apoptotic proteins BCL2 and BIRC5/Survivin, the oncogene MYC , EMT genes [125], and activation of ATF6, resulting in ER stress response and autophagy [126]