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Acid in the stomach is essential for this function, so long-term use of strong acid-suppressing medications such as Aciphex (rabeprazole), Nexium (esomeprazole), Prevacid (lansoprazole), Prilosec (omeprazole), or Protonix (pantoprazole) may contribute to a problem for some individuals, especially when taken for a long period of time

Stable gastric pentadecapeptide BPC 157 studied for in-ammatory bowel disease (PLD-116, PL14736, Pliva) induces nitric oxide synthesis

While well-tolerated, they require careful consideration of potential adverse effects and contraindications (6)

Role of gut microbiota and probiotics in colorectal cancer: Onset and progression