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Extracting biological insights from the Project Achilles genome-scale CRISPR screens in cancer cell lines

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When pathogens invade, plants stimulate ROS production, which is rapidly triggered following detection of a pathogen and may synergistically activate the hypersensitive response (HR) (Paiva and Bozza, 2014), and at the same time enhance thickening of adjacent cell walls to prevent spread of invading pathogens (Wang and Higgins, 2005)

Hence, the diethyl ester of glutathione could be used for decreasing oxidative stress and toxicity.