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Strong localization is observed around the Zn center and extends toward the coordinating atoms of GHB, indicating significant orbital confinement and directional interaction

This is in agreement with previous results showing neopterin-induced Nrf-2 nuclear translocation with increased content of key cytoprotective downstream proteins, including the antioxidant HO-I (it metabolizes heme into biliverdin, a potent antioxidant) in rodent and human cells [17]

For example, a highly favorable thioldisulfide exchange between the C- and N-terminal sites of DsbD was proposed ( k =110 5 M 1 s 1 ), although the kinetics were investigated in an intermolecular fashion via the purified C-terminal (cDsbD) and N-terminal domains of DsbD (nDsbD

Aitboulahsen, M