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Step 3: Support with precursors

We investigated three key aspects of FTD pathophysiology mitochondrial dysfunction, inflammation, and oxidative stress that are important to neurodegeneration

Human leukocytes, including peripheral blood mononuclear cells (PBMCs) and polymorphonuclear leukocytes (PMNs), were isolated from the blood of healthy donors using Histopaque (Sigma-Aldrich, USA)