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Description

Paracrine IGF-1 has a greater effect on mammary gland branching than IGF-1 from endocrine sources (Richards et al., 2004)

Proteins were separated by SDS-PAGE and visualized by coomassie blue staining

In approximately 80% of cases, the upper extremities are also involved, with the tissue accumulation terminating abruptly at the wrists to create a cuffing effect ( FIGURE 1 While often mischaracterized as a rare condition, lipedema selectively impacts a significant yet specific segment of the global population