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Knockdown of gsk3beta increases basal autophagy and ampk signaling in nutrient-laden human aortic endothelial cells

The inhibition of methylation enzymes (DNMTs) with different molecules such as azacitidine and decitabine (drugs used in oncology), can be useful in modifying the malignant phenotype of the cells through re-expression of tumor suppressor genes [8, 47, 48]