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They are not approved for medical use by major regulatory agencies

The selected antigens were analyzed based on their entire sequences to determine which antigens contained a high number of T-cell epitopes

CRISPR-Cas9 whole genome-wide gene-knockout screens for suppressors and enhancers of C9orf72 DPRs in human cells revealed TMX2 as an important protective modifier against toxicity (Kramer et al., 2018)