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Explored in endocrine axis research investigating GH signaling and anabolic pathway modulation

Astrocytes derived from stem cells generated from ALS patients cannot sustain neurones in co-culture

Collectively, these results documented that the interference with Ea-domain glycosylation resulted in a dramatic decrease of intracellular proIGF-1Ea level and hence proIGF-1Ea and mature IGF-1 secretion

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