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FAP-CAR-Ms and FAP-CAR-ZETA-Ms derived from bone marrow inhibited activation of FAP-positive hepatic stellate cells in vivo , promoting extracellular matrix degradation via downregulation of Col1a1 and Acta2 and upregulation of MMP-9 and MMP-13 (89)

PMID: 126 XiangKKalthoffCMnchCJendrossekVMatschkeJ

The high affinity of GHK for copper(II) ions (binding constant K = 10^16.44 M) ensures that copper is transported in a bound, controlled form rather than as a free ion causing oxidative stress

In systemic lupus erythematosus (SLE), which is characterized by chronic activation of self-reactive lymphocytes and myeloid cells, untargeted lipidomics using LC/MS and GC/MS has revealed altered serum concentrations of choline, ACh, phosphocholine, and specific species of PC, lysoPC, and sphingomyelin (192194)