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Figure 2: Pycnogenol improves skin elasticity and prevents moisture decrease Another finding that supports Pycnogenols positive effects on skin barrier function was the increased expression of genes involved in keratinocyte differentiation and barrier formation, including loricrin, indicating that Pycnogenol supplementation was associated with improved formation of cornified envelopes and, thus, preserved skin hydration by reducing trans-epithelial water loss

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The same group also found that an external workload-matched regime (employing double the load such that sets averaged only ~ 6 reps to failure) produced a nearly identical pattern of glycogen use and immediate post-exercise recovery