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Overall, downstream effects of an abnormal proteome lead to a vicious cycle of disruption in proteostasis, including endoplasmic reticulum stress, mitochondrial dysfunction, and synapse destruction within motor neurons [213]

Caffeine administration mitigates chronic stress-induced behavioral deficits, neurochemical alterations, and glial disruptions in rats

Microneedling is also a safe procedure to perform on skins of color [106]

Methods: In this retrospective analysis from a prospective observational single center cohort study, we included MRI data from 216 consecutive acute ischemic stroke patients undergoing endovascular therapy (EVT)