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*Correspondence: Bin Ding, [email protected] These authors have contributted equally to this work This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Key points Sickle cell disease is associated with semen parameter abnormalities in the majority of patients

Hydroxocobalamin, however, is the most biologically active form of Vitamin B12

Many of the physicians who spoke with the Migraine World Summit have seen even better results among their patients than those of the PREEMPT Trial