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Safety Profile Across all six human trials and the extensive preclinical work, the safety picture is quite clean: No serious adverse events attributed to the compound No effect on IGF-1 No impairment of glucose tolerance or insulin sensitivity No genotoxic activity Most common side effects: mild injection site irritation, occasional headache or fatigue all transient This is genuinely one of the better-characterized peptides from a safety standpoint, largely because it actually went through a formal development process with proper clinical oversight

Reference lists were also examined for any additional relevant studies not identified through the search

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Combined use should always follow clinical assessment and should not replace investigation of underlying causes