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OXPHOS is often upregulated in cancer stem cells and drug-resistant tumors [81, 83] and our observations are in line with recent findings describing that the treatment of metastatic breast cancer with Palbociclib elicits increased OXPHOS as a resistance mechanism that can be countered pharmacologically [82]

[Google Scholar] 71.Popivanov I, Petkova T, Doycheva V, Doychinova T, Angelov I, Shalamanov D

So pushing the body when it isnt ready for exercise will just cause more fatigue and can even result in a health collapse