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stimulated macrophage cell activation, leading to the upregulating of pro-inflammatory cytokines, including TNF-, IL-6, and IL-10

One animal study examining the effects of aloe vera on gastric acid secretion and gastric mucosal health found that aloe vera balanced acid secretion and, at low doses, protected mucosa from temporary influxes of excess gastric acid

Its intrinsic properties, including high cell permeability, the ability to easily cross both the bloodbrain and placenta barriers, and its role as an endogenous reservoir of free radical scavengers (with indirect extra activities), confer it beneficial uses as an adjuvant in the biomedical field