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In nutraceuticals it serves four objectives: protecting acid-sensitive ingredients (such as probiotics and enzymes) from gastric degradation, targeting a specific segment of the gastrointestinal tract such as the colon, sustaining delivery over several hours, and improving the oral bioavailability of poorly soluble compounds such as curcumin, CoQ10, and fat-soluble vitamins.[1] Technologies range from established platforms (HPMC delayed-release capsules, enteric coatings) to newer approaches such as multi-layer beadlets, liposomal encapsulation, and phytosome complexes

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Intermittent fasting (IF), defined as every-other-day feeding, has been shown to extend lifespan and enhance health status in mammals [10, 11]