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It is not known yet whether the pigmented material serves a protective function or is related to phagocytosis only

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451 In streptozotocin (STZ)-induced diabetic rat and mouse models, elevated expression of P2X2 and P2X3 receptors in the DRG, along with increased current density and P2X4 receptor expression on satellite glial cells, indicates that P2X4 receptor activation in the DRG significantly contributes to DPN-induced mechanical pain hypersensitivity (Fig

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Data availability All data supporting the findings described are available in this paper and in the Supplementary Information

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