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Polyglutamate directed coupling of bioactive peptides for the delivery of osteoinductive signals on allograft bone

However, blocking NF-B may bring about undesirable side effects, such as the broad suppression of innate immunity due to the lack of specificity of the relevant treatment and the significance of NF-B in cellular homeostasis (66)

Overall, ICARIA-MM enrolled a more refractory patient population compared with APOLLO: at baseline, patients in ICARIA-MM had received more prior therapy lines (median, 3 vs

[6] [7] For patients with neurological symptoms, hydroxocobalamin 1mg IM is given on alternate days until no further improvement, followed by maintenance injections of 1mg every two to three months