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In addition, ER also mediates the expression of glutathione S-transferase mu 3 (GSTM3) to resist cytotoxicity caused by drug therapy and to protect the drug-resistant cells

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Evidence of an enzyme defense barrier at the nuclear envelope

However, in a nested case study, it was found that plasma VitB12 compared with the highest quintile and lowest quintile breast cancer, the risk of breast cancer increased by 64% (95% CI 1.172.29, P value = 0.02), the higher the level of VitB12 in plasma, the higher the risk of breast cancer