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Human and experimental toxicology of diquat poisoning: toxicokinetics, mechanisms of toxicity, clinical features, and treatment

This assumption is confirmed by clinical observations pointing to increased levels of peripheral blood CCR4 + CD4+ cells in sarcoidosis, as well as elevated concentrations of CCL17 chemokines both in the blood serum and at the site of granuloma formation (128)

Betz RC, Petukhova L, Ripke S, Huang H, Menelaou A, Redler S, Becker T, Heilmann S, Yamany T, Duvic M, Hordinsky M, Norris D, Price VH, Mackay-Wiggan J, de Jong A, DeStefano GM, Moebus S, Bhm M, Blume-Peytavi U, Wolff H, Lutz G, Kruse R, Bian L, Amos CI, Lee A, Gregersen PK, Blaumeiser B, Altshuler D, Clynes R, de Bakker PIW, Nthen MM, Daly MJ, Christiano AM (2015) Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci