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It should only be administered by a healthcare professional

Vitamin B12 injections may benefit people experiencing: Fatigue Vitamin B12 deficiency Low energy Poor absorption Pernicious anaemia Certain gastrointestinal conditions Vegan or vegetarian diets A consultation helps determine whether treatment is appropriate

Many other insights into the enzyme were gained from an analysis of the structure, including the presence of a bimodal switch in the orientation of the catalytic nucleophile and the open conformation of the lid loop region of the enzyme (West et al., 2013b)