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Perhaps the most exciting treatment study in autism published recently involved a mouse model and treatment with probiotics [22]

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SURMOUNT-MAINTAIN (Horn 2026, 112 weeks): continued top dose -21.9% vs 5 mg step-down -16.6% vs placebo -9.9%, rescue therapy 8/25/67%: Aronne JAMA 2024

A single point mutation (C 334 V) improved recombinant expression in human cells, enhanced protein stability, prevented dimerisationpreviously responsible for yield losses in Npand increased peptidolytic activity by 20%