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In a Phase I crossover study involving healthy volunteers (NCT04384666), the pharmacokinetic profile of a single dose of LY03003 (28 mg) injected intramuscularly was compared with a 7-day regimen of Neupro, indicating that the injectable system could provide sustained drug release over an extended period 140

Gao P, Tian Y, Xie Q, Zhang L, Yan Y, Xu D (2020) Manganese exposure induces permeability in renal glomerular endothelial cells via the Smad2/3-Snail-VE-cadherin axis

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By the time the body tries to reassemble those pieces, the benefit of the intact glutathione molecule is lost