glutathione tumor Tumor-targeted oxidation catalysis with ruthenium nanoreactors against hypoxic osteosarcoma Functions of glutathione-degrading enzymes in

Of a particular interest, poly(lactide-co-glycolide) (PLGA) is a biocompatible and biodegradable polyester, which is used in several FDA-approved products in the form of microspheres and other pharmaceutical dosage forms 2,3

In the body, dietary phenolic compounds are subjected to the same processes as drugs, that is, they have to be taken up in vivo (absorption), they are distributed in tissues and organs, they are typically metabolized and finally eliminated (Figure 1)

For example, compared to the control, 200 M KI concentration reduced total plant dry matter and plant height, respectively, by 42 and 46% in Red Rubin, and both by 73% in Tigullio

doi: 10.3389/fphar.2012.00089 Received 03 February 2012 Accepted 25 April 2012 Published 18 May 2012 Volume 3 - 2012 Edited by Jaime Kapitulnik, The Hebrew University of Jerusalem, Israel Reviewed by Dora Brites, University of Lisbon, Portugal