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These companion papers demonstrate that some tumors in vivo are really limited by the chemical processes that require oxygen to get the aspartate they need to grow, which can affect their sensitivity to drugs like metformin, Vander Heiden says

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The citation is: Leah Halls and Chad M

In a phase 1b trial (NCT01583283), ricolinostat with lenalidomide and dexamethasone yielded a 55% overall response rate in patients with relapsed/refractory multiple myeloma

Serum levels of sRAGE, the soluble form of receptor for advanced glycation end products, are associated with inflammatory markers in patients with type 2 diabetes