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Description

Inflammation 40 (5), 14751486

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10.1016/j.jep.2010.06.027 148 YangL

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It arises from an abnormally expanded CAG trinucleotide repeat encoding the elongated polyglutamine (polyQ) within exon 1 of Huntingtin ( HTT ) gene, which results in the production of toxic mutant huntingtin proteins (mHTT) that accumulate in neurons, particularly in the striatum and cortex (Genetic Modifiers of Huntingtons Disease Consortium, 2019)

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Fade dark patches and spots

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