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Among these treatments, lifestyle changes should be the main focus for IR treatment, with nutritional intervention to decrease calories, avoidance of carbohydrates, and focusing on aliments with low glycemic index (including vegetables, fruits, whole-grain products, nuts, lean meats or beans) to provide higher fiber, vitamins, healthy fats and protein are particularly helpful for people trying to improve insulin sensitivity

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An in-vivo approach is being studied, meaning the gene therapy is delivered directly into the body to target liver cells

This way, the change in the elasticity and density of the skin becomes more apparent