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Genetic recombinant experiments were reviewed by Safety Officer in RIKEN, and approved by the director of RIKEN Wako Campus (approval number: 2022-029(1))

The improvement of barrier integrity by the regulation of tight junction protein expression or through other mechanisms has shown promising results with improvement of the disease symptoms in UC, CD, and metabolic diseases

In fact, recent research suggests that when combined, metabolically active folate and supplemental vitamin B12 are effective for supporting cognition, energy production, and neural tissue

Discussion The glutathione pools of the cytosol and the IMS are connected by the porins in the OMM In this study, we developed an approach to investigate the dynamics of E GSH in different cellular compartments