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Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review

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From medial to lateral, they are the fastigial, interposed, and dentate nuclei, all of which link the cerebellum to the rest of the brain and spinal cord [24]

It was first reported 20 years ago that systemic IGFs could cross the bloodbrain barrier (BBB), when labeled IGFs were infused into the common carotid arteries of adult rats, and they were later on detected in the choroid plexus, median eminence, brain arterioles, and parenchyma[64]