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identified that specific gut microbes inhibit remodeling-associated cytokines (IL-4, IL-5, IL-9, IL-13) through SCFA production, mitigating airway wall thickening ( Lactobacillus rhamnosus (Lr) administration reduced leukocyte infiltration, bronchial hyperreactivity, and remodeling markers (IL-4, IL-5, IL-13, STAT6, GATA3, IL-17, IL-21, IL-22, STAT3, RORt) in asthma-COPD overlap syndrome (Vasconcelos et al., 2023)

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