glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of PDF) Glutathione responsive iNOS inhibiting

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of PDF) Glutathione responsive iNOS inhibiting
Brand: equiscorp.hu
SKU: 85438404997
Price: 27.00 USD
Availability: InStock
Rating: 4.6012 (20 reviews)

PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis Dual pH redox responsive hyperbranched polymeric nanocarriers with TME trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer Scientific Reports Glutathione Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy ACS Nano Glutathione responsive prodrug conjugates for image guided combination in cancer therapy ScienceDirect

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Description

Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm