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There is anecdotal evidence and some early research suggesting that by improving the health of the follicles and reducing oxidative stress, NAD+ may slow the progression of graying hair, though it is not a cure for existing grays

Such a condition is centered on the removal of inhibition of the carnitine handling enzyme CPT1 via the specific down-regulation of acetyl-CoA carboxylase 2 (ACC2), with a strong reduction of the malonyl-CoA pool responsible for CPT1 inhibition (Koundouros and Poulogiannis, 2020)

doi:10.1105/tpc.11.6.1153 [PubMed] 20

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