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Specifically, PER3 expression was significantly reduced and circadian rhythmicity disrupted in workers on multiple consecutive NS compared to those on a single NS or daytime shifts 209

The reality for most users sits somewhere in the middle

References & Medical Sources The following reputable medical organizations and clinical resources were consulted in preparing this educational guide on Wilson's disease: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)- Wilson's Disease Overview National Institutes of Health (NIH) Genetic and Rare Diseases Information Center (GARD) World Health Organization (WHO)- Essential Medicines and Rare Disease Guidance U.S